Generic Formulary
Cardio Vascular System
Sub Group: 
International Brand Name: 
12.5 MG/ 25 mg
Unit of Packing: 
In treatment of: 
Management of Hyper Tension(HTN);Management of Angina Pectoris
Adverse Effects: 
1.Nightmares 2.Sleep disturbances 3.Gastrointestinal problems 4.Nausea 5.Tiredness 6.Bradycardia 7.Rash 8.Orthostatic hypotension 9.Dizziness 10.Fatigue
1.Hypersensitivity to the drug 2.Uncontrolled heart failure 3.Second or third degree heart block 4.Cardiogenic shock 5.Severe Bradycardia 6.Phaeochromocytoma
Special Precaution: 
1.Cardiac insufficiency 2.First degree heart block 3.Prinzmetal angina 4.Raynaud`s syndrome 5.The drug should be gradually withdraw with caution over a period of 1 to 2weeks 6.Chronic obstructive pulmonary diseases 7.Use with caution in General Anaesthesia
Ace inhibitors: Enhanced hypotensive effect. NSAIDs: Antagonise hypotensive effect. Antidiabetics: Enhanced hypoglycaemic effect. Clonidine: Increased risk of withdrawal hypertension. Cardiac glycoides: Increased peripheral vasoconstriction. Ergotamine: Increased peripheral vasoconstriction.Sympathomimetics: Severe hypertension.
200mg once daily. Increased by each 200mg up to 600mg at 2weeks intervals if required based on patient`s response.

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