Generic Formulary
Central Nervous System
Sub Group: 
Anti Depressants
International Brand Name: 
Celexa,Cipramil,Citrol, Citabax,citaxin,Citalec, Celapram,Ciazil
10 MG/10 MG/20 MG/40 MG
Unit of Packing: 
In treatment of: 
Treatment of depression
Adverse Effects: 
1. Nausea 2. Diarrhoea 3. Insomnia 4. Somnolence 5. Dry mouth 6. Fatigue 7. Increased sweating 8. Tremor 9. Dizziness 10. Agitation 11. Dyspepsia 12. Anorexia 13. Abdominal pain 14. Dysmenorrhea 15. Amenorrhea 16. Ejaculation disorder 17. Impotence 18. Polyuria 19. Upper respiratory tract infection 20. Fever 21. Myalgia 22. Arthralgia
1.Hypersensitivity to Citalopram, 2.Patient on MAOI (Monoamine oxidase inhibitor) therapy.
Special Precaution: 
1. Hepatic impairment 2. Renal impairment 3. Myocardial infarction 4. Cardiac failure 5. Epilepsy 6. Mania 7. Alcoholics 8. Patient on MAOI therapy (Discontinue the MAO inhibitor at least 2 weeks before Citalopram is started) 9. Use cautiously in patient at risk for suicide 10. Use caution while driving vehicle, operating machine and activities requiring mental alertness or judgment
Ketoconazole, itraconazole, macrolide antibiotics and omeprazole: Decrease clearance of citalopram. Metoprolol: Increase plasma level of metoprolol. Azole antifungals: Increase citalopram plasma levels . Beta-blockers: Increase effect of beta-blocker; reduce initial beta blocker dose. Carbamazepine: Decrease citalopram plasma levels; increase serum carbamazepine levels. Imipramine: Increase drug metabolite (desimipramine) by 50% Lithium: Possible serotonergic effects of citalopram Macrolide antibiotics (e.g.erythromycin): Increase citalopram plasma levels MAO inhibitors: Possible serious and sometimes fatal reactions, including hyperthermia, rigidity, myoclonus, autonomic instability, mental status changes (extreme agitation, delirium, coma)
Adult: Initial dose: 10 mg / day, dose can be increased to 20 mg / day if sufficient response does not occur after 1 week

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