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Dimenhydrinate
Product:
Dimenhydrinate
Formulary:
Generic Formulary
Category:
Central Nervous System
Sub Group:
Antiemetics & Antinauseants
International Brand Name:
Dramamine,Gravol,Gravamin,Vertirosan
Dosages:
50 MG
Unit of Packing:
Tablets
In treatment of:
Prevention & treatment of motion sickness;treatment of nausea and vertigo caused by Meniere's diseases
Adverse Effects:
1.Sedation
2.Dizziness
3.Dry mouth
4.Drowsiness
5.Headache
6.Confusion
7.Nervousness
8.Tightness of chest
9.Tachycardia
10.Blurred vision
11.Abdominal discomfort
12.Constipation
13.Anaphylaxis
14.Anorexia
Contraiindication:
Hypersensitivity to Dimenhydrinate or related drug
Special Precaution:
1.Seizure disorder
2.Prostate hypertrophy
3.Acute angle closure glaucoma
4.Urinary retention
5.Hypotension
6.Asthma
7.Hepatic impairment
8.Porphyria
9.Hypertension
10.Irregular heart beat
Interaction:
Alchohol & other CNS depressants like barbiturates, analgesics, sedatives neuroleptics: CNS depressant effect enhanced.
MAOIs, Atropine & TCAs: Antimuscarinic effect enhanced.
Aminoglycosides: Ototoxicity masked, irreversible damage may occur.
Aminophylline, Hydrocortisone, Phenothiazines and some soluble barbiturates: Incompatible with these in solution.
Servings:
Adults: 50 - 100 mg 6 - 8 hours daily
For motion sickness drug should be administered half an hour before traveling.
Treatment of nausea and vomiting in Meniere`s disease: 50 mg IM for acute attack
Maintenance dose: 75 - 150 mg / day in 3 divided doses
Children: 1.5 mg / kg / day in 3 divided doses.
