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Divalproex Sodium
Product:
Divalproex Sodium
Formulary:
Generic Formulary
Category:
Central Nervous System
Sub Group:
Anti Convulsants
Dosages:
250 MG/500mg
Unit of Packing:
Tablets
In treatment of:
Mgt of Psychiatric conditions
Adverse Effects:
1.Headache
2.Ataxia
3.Tremor
4.Dizziness
5.Nausea
6.Vomiting
7.Somnolence
8.Abdominal cramps
9.Diarrhoea
10.Anorexia
11.Loss of hair
12.Pancreatitis
13.Hyperammonaemia
14.Thrombocytopenia
Contraiindication:
1.Hypersensitivity to Divalproex
2.Hepatic impairment
Special Precaution:
1.Mental retarded children taking antiepileptic drugs
2.Congenital metabolic disorders
3.Slowly withdraw the drug with caution
4.Use with caution when driving vehicle, operating machine or performing other hazardous activities
5.Monitor liver function before and during the treatment
Servings:
Adult:
Anticonvulsant: Initial dose: 10 - 15 mg / kg / day in 3 divided doses. Dose can be increased by 5 - 10 mg /kg/day every 7 days until seizures are controlled.
Maximum dose: 60mg / kg/day
Mania: 750 mg / day in divided doses
Migraine prophylaxis: 500mg / day in 2 divided doses if needed dose can be increased up to 1 g.
CHILDREN above 10 years:
Anticonvulsant: Initial dose: 10 - 15 mg / kg / day in 3 divided doses. Dose can be increased by 5 - 10 mg /kg/day every 7 days until seizures are controlled.
Maximum dose: 60mg / kg/day
