DOBUTAMINE

Product: 
DOBUTAMINE
Formulary: 
Generic Formulary
Category: 
Cardio Vascular System
Sub Group: 
INOTROPIC AGENTS,DRUGS USED IN CHF
International Brand Name: 
Dosages: 
50MG/4ML; 250 mg/20 ml
Unit of Packing: 
Vial
In treatment of: 
Mgt of acute Heart failure
Adverse Effects: 
1. Hypertension 2. Increased heart rate 3. Premature ventricular contraction 4. Chest pain 5. Palpitation 6. Hypotension 7. Episodes of asthma 8. Hypersensitivity reactions 9. Nausea 10. Vomiting 11. Headache
Contraiindication: 
1. Hypersensitivity to the drug 2. Hypertrophic subaortic stenosis
Special Precaution: 
1. Hypertension 2. Atrial fibrillation 3. Monitor ECG and blood pressure during therapy 4. Hypovolemia should be corrected before therapy using suitable volume expanders 5. Drug may precipitate an exaggerated pressor response 6. Do not mix with sodium bicarbonate
Interaction: 
Bretylium: Potentiates its action resulting in arrhythmias. Halogenated hydrocarbon anaesthetics: Risk of serious arrhythmias. Oxytoxic drugs: May cause persistent hypertension. TCAs: Use with caution since efficacy of vasopressor enhanced. Phentolamine & Prazosin: Antagonistic action. Nitroprusside: Additive effect.
Servings: 
2 to 20mcg/kg/minute as I.V. infusion. Dosage adjustment is based on patient`s response. Maximum dose: 40mcg/kg/minute.

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