Generic Formulary
Sub Group: 
International Brand Name: 
Ellence,Pharmorubicin , Epirubicin Ebewe
10 mg/ 50 mg
Unit of Packing: 
In treatment of: 
Treatment of Breast Cancer & adjuvant treatment of early Breast Cancer w//+ve Lymph nodes
Adverse Effects: 
1. Nausea 2. Vomiting 3. Difficulty in breathing 4. Closing of the throat 5. Bone marrow suppression 6. Bruising or unusual bleeding 7. Tarry stools 8. Fever 9. Chills 10. Congestive heart failure 11. Diarrhea 12. Loss of appetite 13. Facial flushing 14. Darkening of skin and nails 15. Alopecia 16. Red urine 17. Leukemia 18. Hyperpyrexia 19. Amenorrhea 20. Anaphylaxis 21. Photosensitivity 22. Premature menopause 23. Thrombocytopenia 24. Neutropenia 25. Leucopenia 26. Conjuctivitis 27. Keratitis 28. Swelling of the lips, tongue and face
1. Hypersensitivity to the drug 2. Hypersensitivity to other anthracycline and anthracenediones 3. Hepatic impairment 4. Myocardial insufficiency 5. Myocardial infarction 6. Severe arrhythmia 7. Cardiac disease 8. Previous therapy with anti tumor drugs in high doses
Special Precaution: 
1. Previous extensive radiotherapy 2. Bone infiltration by tumor 3. Recent immunizations
Intravenous- Adults- 135 mg/metre square as a single agent and 120mg/metre square in combination every 3 to 4 weeks for the treatment of breast cancer 100mg/metre square every 3 to 4 weeks for the treatment of early breast cancer

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