Generic Formulary
Sub Group: 
International Brand Name: 
Urometaxan , MESNEX , Uromitexan
100 MG
Unit of Packing: 
In treatment of: 
Treatment of acute Lymphoblastic Leukaemia and Myeloid Lukaemias
Adverse Effects: 
1. Bad taste in mouth 2. Diarrhea 3. Soft stool 4. Headache 5. Nausea 6. Vomiting 7. Fatigue 8. Blood in urine 9. Skin rash 10. Itching 11. Hypotension 12. Tachycardia 13. Depression 14. Limp pain
Contraindicated in patients with hypersensitivity to mesna and to other thiol containing compounds
Special Precaution: 
1. With ketone urea 2. Engaging in activities which require alertness such as driving or using machinery
Intravenous- Adults-Mesna dose depend upon the amount of ifosfamide and cyclophosphamide that a patient receives. The standard dose depends equal to 20% of the total ifosfamide given at three separate time interval through a vein infused over at least 5 minute, first dose is right before the ifosfamide, often referred to as 0 hr, the 2nd dose is 4 hr after the start of the infusion and the 3rd dose is 8 hrs after the start of infusion. Mesna can also be administered through orally by mixing with flavoured drink like grape juice, cola, chocolate and milk etc.

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