Generic Formulary
Genito Urinary System
Sub Group: 
International Brand Name: 
Unit of Packing: 
In treatment of: 
Cervical ripening,postcoital contraception,termination of pregnency (49 days or less duration),termination of pregnency up to 63 days,induction of labour following intrauterine foetal death, termination of pregnancy between 13-24 wk of gestation,softening and dilatation of cervix prior to surgical termination of pregnency
Adverse Effects: 
1.Dizziness 2.Headache 3.Diarrhea 4.Nausea 5.Vomiting 6.Back pain 7.Feeling tired 8.Hot flashes 9.Abdominal pain 10.Anorexia 11.Vginal bleeding 12.Bad-smelling vaginal discharge 13.Fainting 14.Irregular heartbeat 15.Palpitations 16.Chest pain 17.Fever 18.Redness, blistering, peeling or loosening of the skin, including inside the mouth 19.Skin rash 20.Uterine infections
1.Hypersensitivity to Mifepristone 2.Ectopic pregnancy 3.Adrenal failure 4.Patient on long term corticosteroid therapy 5.Haemorrhagic disorder 6.Concurrent anticoagulant therapy 7.Inherited porphyria 8.Hepatic impairment 9.Renal impairment
Special Precaution: 
1.Asthma 2.Chronic obstructive pulmonary diseases 3.Cardiovascular diseases 4.Smoking 5.Alcoholism 6.Should be taken prior to and during surgical abortion to prevent rhesus immunisation.
Ketoconazole, itraconazole, erythromycin, and grape fruit may inhibit mifepristone metabolism. Rifampicin, dexamethasone, phenytoin, phenobarbital, carbamazepine induce mifepristone`s metabolism.
Adult: 1.Cervical ripening: 50 - 600mg to be taken 24 - 30 hour before surgery. 2.Postcoital contraception: 600mg as single dose within 3 days after intercourse. 3.Once a month contraceptive pill: 200mg as single dose on the second day after mid cycle. 4.Termination of pregnancy up to 49 days: 600 mg as single dose and after 2 days takes Misoprostol 400mcg as single dose. 5.Termination of pregnancy up to 63days: 600 mg as single dose and after 36 - 48 hours take Gemeprost vaginally. 6.Termination of pregnancy between 13 - 24 weeks of gestation: 600mg as single dose to be taken 36 - 48 hours before prostaglandin therapy 7.Induction of labour following intrauterine fetal death: 600mg / day for 2 days. 8.Softening and dilatation of cervix before surgical termination of pregnancy: 600 mg as single dose is given 36 - 48 hours before surgery.

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